2,308 research outputs found
Editorial: Controversies and solutions in environmental sciences: Addressing toxicity of sediments and soils
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2007 Ecomed Publishers
Effect of arm movement on balance performance in children: role of expertise in gymnastics
OBJECTIVE: Studies have shown that balance performance is better in gymnasts compared to age-/sex-matched controls and further studies revealed superior performance when arms were free to move during assessment of balance. However, it is unknown whether free arm movement during balance testing differentially affects balance performance with respect to sports expertise (i.e., gymnasts are less affected than age-/sex-matched controls). Therefore, we investigated the effect of arm movement on balance performance in young female gymnasts compared to age-/sex-matched controls while performing balance tasks with various difficulty levels. RESULTS: In both samples, balance performance (except for the timed one-legged stance) was significantly better during free compared to restricted arm movement conditions and this was especially observed in the highest task difficulty condition of the 3-m beam walking backward test. These findings revealed that balance performance is positively affected by free arm movements, but this does not seem to be additionally influenced by the achieved expertise level in young gymnasts
A BeppoSAX observation of the super-soft source CAL87
We report on a BeppoSAX Concentrator Spectrometer observation of the
super-soft source (SSS) CAL87. The X-ray emission in SSS is believed to arise
from nuclear burning of accreted material on the surface of a white dwarf (WD).
An absorbed blackbody spectral model gives a chi^2_v of 1.18 and a temperature
of 42 +/- ^13 _11 eV. However, the derived luminosity and radius are greater
than the Eddington limit and radius of a WD. Including an O viii edge at 0.871
keV gives a significantly better fit (at > 95% confidence) and results in more
realistic values of the source luminosity and radius. We also fit WD atmosphere
models to the CAL87 spectrum. These also give reasonable bolometric
luminosities and radii in the ranges 2.7-4.8 10^{36} erg/s and 8-20 10^7 cm,
respectively. These results support the view that the X-ray emission from CAL87
results from nuclear burning in the atmosphere of a WD.Comment: 4 pages. Accepted for publication in A&A (Letters
Interferometric measurement of resonance transition wavelengths in C IV, Si IV, Al III, Al II, and Si II
We have made the first interferomeric measurements of the wavelengths of the
important ultraviolet diagnostic lines in the spectra \ion{C}{4} near 155 nm
and \ion{Si}{4} near 139 nm with a vacuum ultraviolet Fourier transform
spectrometer and high-current discharge sources. The wavelength uncertainties
were reduced by one order of magnitude for the \ion{C}{4} lines and by two
orders of magnitude for the \ion{Si}{4} lines. Our measurements also provide
accurate wavelengths for resonance transitions in \ion{Al}{3}, \ion{Al}{2}, and
\ion{Si}{2}.Comment: 6 pages, 2 figures, 1 tabl
Murine cytomegalovirus inhibits interferon γ-induced antigen presentation to CD4 T cells by macrophages via regulation of expression of major histocompatibility complex class II-associated genes
CD4 T cells and interferon γ (IFN-γ) are required for clearance of murine cytomegalovirus (MCMV) infection from the salivary gland in a process taking weeks to months. To explain the inefficiency of salivary gland clearance we hypothesized that MCMV interferes with IFN-γ induced antigen presentation to CD4 T cells. MCMV infection inhibited IFN-γ-induced presentation of major histocompatibility complex (MHC) class II associated peptide antigen by differentiated bone marrow macrophages (BMMΦs) to a T cell hybridoma via impairment of MHC class II cell surface expression. This effect was independent of IFN-α/β induction by MCMV infection, and required direct infection of the BMMΦs with live virus. Inhibition of MHC class II cell surface expression was associated with a six- to eighffold reduction in IFN-γ induced IAb mRNA levels, and comparable decreases in IFN-γ induced expression of invariant chain (Ii), H-2Ma, and H-2Mb mRNAs. Steady state levels of several constitutive host mRNAs, including β-actin, cyclophilin, and CD45 were not significantly decreased by MCMV infection, ruling out a general effect of MCMV infection on mRNA levels. MCMV effects were specific to certain MHC genes since IFN-γ-induced transporter associated with antigen presentation (TAP)2 mRNA levels were minimally altered in infected cells. Analysis of early upstream events in the IFN-γ signaling pathway revealed that MCMV did not affect activation and nuclear translocation of STAT1α, and had minor effects on the early induction of IRF-1 mRNA and protein. We conclude that MCMV infection interferes with IFN-γ-mediated induction of specific MHC genes and the Ii at a stage subsequent to STAT1α activation and nuclear translocation. This impairs antigen presentation to CD4 T cells, and may contribute to the capacity of MCMV to spread and persist within the infected host
Study of led lamp power supply
В данной статье исследуется источник питания светодиодного светильника с высокимкоэффициентом мощности. Использована микросхема корректора коэффициента мощности компании STMicroelectronics L6561 в обратноходовой топологии. С помощью этой микросхемы упрощается построение источника питания, учитывая стандарты энергосбережения и требования к уровню вносимых в питающую сеть искажений.In this article, we investigate the LED lamp power supply with a high power factor. To implement this, the power factor corrector of STMicroelectronics L6561 is used in the fly-back topology. With the help of this IC simplifies the construction of the power supply, considering energy-efficiency standards and requirements for the level introduced into the mains distortion.Fir filter design using frequency sampling method
Gravitational Wave Memory of Gamma-Ray Burst Jets
Gamma-Ray Bursts (GRBs) are now considered as relativistic jets. We analyze
the gravitational waves from the acceleration stage of the GRB jets. We show
that (i) the point mass approximation is not appropriate if the opening
half-angle of the jet is larger than the inverse of the Lorentz factor of the
jet, (ii) the gravitational waveform has many step function like jumps, and
(iii) the practical DECIGO and BBO may detect such an event if the GRBs occur
in Local group of galaxy. We found that the light curve of GRBs and the
gravitational waveform are anti-correlated so that the detection of the
gravitational wave is indispensable to determine the structure of GRB jets.Comment: Revtex4, 10 pages, 6 figures, Fig.2 and Fig.3 replaced, minor changes
to text in Sec.I and Sec.V, typos corrected, some reference added, Version to
be published in PR
Development and characterization of a Rift Valley fever virus cell–cell fusion assay using alphavirus replicon vectors
AbstractRift Valley fever virus (RVFV), a member of the Phlebovirus genus in the Bunyaviridae family, is transmitted by mosquitoes and infects both humans and domestic animals, particularly cattle and sheep. Since primary RVFV strains must be handled in BSL-3+ or BSL-4 facilities, a RVFV cell–cell fusion assay will facilitate the investigation of RVFV glycoprotein function under BSL-2 conditions. As for other members of the Bunyaviridae family, RVFV glycoproteins are targeted to the Golgi, where the virus buds, and are not efficiently delivered to the cell surface. However, overexpression of RVFV glycoproteins using an alphavirus replicon vector resulted in the expression of the glycoproteins on the surface of multiple cell types. Brief treatment of RVFV glycoprotein expressing cells with mildly acidic media (pH 6.2 and below) resulted in rapid and efficient syncytia formation, which we quantified by β-galactosidase α-complementation. Fusion was observed with several cell types, suggesting that the receptor(s) for RVFV is widely expressed or that this acid-dependent virus does not require a specific receptor to mediate cell–cell fusion. Fusion occurred over a broad temperature range, as expected for a virus with both mosquito and mammalian hosts. In contrast to cell fusion mediated by the VSV-G glycoprotein, RVFV glycoprotein-dependent cell fusion could be prevented by treating target cells with trypsin, indicating that one or more proteins (or protein-associated carbohydrate) on the host cell surface are needed to support membrane fusion. The cell–cell fusion assay reported here will make it possible to study the membrane fusion activity of RVFV glycoproteins in a high-throughput format and to screen small molecule inhibitors for the ability to block virus-specific membrane fusion
Anaerobic starvation survival of marine bacteria
Starvation affects marine bacteria also under anaerobic conditions. Some basic data obtained for anaerobic starvation survival of a fermentative and a sulfaterespiring strain indicate substantial differences. The fermentative strain, Listonella (= Vibrio) anguillarum, responded to, nutrient depletion with rapid reduction of their cell size (dwarfing) and decline of viable cell counts by three orders of magnitude. The sulfate-respiring Desulfovibrio vulgaris showed only minor reductions of the cell sizes and no loss of viability. Whereas a drastic decline of cellular protein concentrations in this strain indicated strong endogeneous respiration, starved cells of the fermenting Vibrio sp. showed increasing levels of protein after an initial decrease
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